| 产品详情 |
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| Antigenic Specificity | SKP1, C-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 85 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human SKP1 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and protein from cell lysates (using HeLa, NIH-3T3, and others). Coimmunoprecipitation of cyclin A and Cuol1 may occur. An 18.5 kDa band corresponding to human SKP1 is detected. Most cell lines expressing SKP1 can be used as a positive control. Researchers should determine optimal titers for other applications. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human SKP1. Cross reactivity is expected against mouse SKP1 based on a high degree of sequence homology. Cross reactivity with other SKP1 proteins or SKP1 from other sources is not known. |
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| Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 152-163 of Human SKP1 (C-terminus) coupled to KLH. |
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| Other Names | rabbit anti-SKP1 Antibody, Cyclin A/CDK2 associated protein p19 antibody, EMC 19 antibody, OCP 2 antibody, p19skp1 antibody, RNA polymerase II elongation factor like protein antibody, S phase kinase associated protein 1 antibody |
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| Gene, Accession # | SKP1, Gene ID: 6500, NCBI: 52783797, UniProt: P63208 |
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| Catalog # | 100-401-A08 |
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| Price | |
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| Order / More Info | SKP1, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Michel,J.J. and Xiong,Y. (1998) Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ. 9 (6), 435-449.Ohta,T., Michel,J.J., Schottelius,A.J. and Xiong,Y. (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol. Cell 3 (4), 535-541.Zhang,H., Kobayashi,R., Galaktionov,K. and Beach,D. (1995) p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell 82 (6), 915-925. |
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