| 产品详情 |
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| Antigenic Specificity | NFkB p65 (RelA) Phospho S529 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 75 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. Anti-phospho NFkB antibody reacts human pS529 p65 and shows minimal reactivity by western blot with non-phosphorylated p65 and minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide. Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-NFkB p65 (RelA) Phospho S529 Antibody was prepared from monospecific antiserum by delipidation and defibrination. This phospho specific polyclonal antibody is specific for phosphorylated pS529 human p65. Reactivity with non-phosphorylated p65 is minimal. Cross reactivity with pS529 phosphorylated p65 from mouse, rat or other species has not been determined. |
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| Immunogen | NFkB p65 (Rel A) peptide corresponding to a region near phospho Serine 529 of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). |
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| Other Names | rabbit anti-NFkB p65 pS529 Antibody, rabbit anti-RelA pS529 Antibody, NFKB, nfkb, NF-kB, NF-kappaB, NFkappaB |
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| Gene, Accession # | RELA, Gene ID: 5970, NCBI: 223468676, UniProt: Q04206 |
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| Catalog # | 100-401-266 |
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| Price | |
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| Order / More Info | NFkB p65 (RelA) Phospho S529 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Ashikawa K, Majumdar S, Banerjee S, Bharti AC, Shishodia S, and Aggarwal BB (2002) Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation. J Immunol 169-11: 6490-7.Shakibaei M, Buhrmann C, Mobasheri A. (2011) Anti-inflammatory and anti-catabolic effects of TENDOACTIVE(R) on human tenocytes in vitro. Histol. Histopathol. Sep;26(9):1173-1185. Shakibaei M, John T, Schulze-Tanzil G, et al. (2007) Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis. Biochem. Pharmacol. 2007 May 1;73(9):1434-1445. Shakibaei M, John T, Schulze-Tanzil G, et al. (2007) Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis. Biochem. Pharmacol. May 1;73(9):1434-1445.Castier Y, Ramkhelawon B, Riou S, et al. (2009) Role of NF-kappaB in flow-induced vascular remodeling. Antioxid. Redox Signal. 2009 Jul;11(7):1641-1649. Zhao L, Lee JY, Hwang DH. (2008) The phosphatidylinositol 3-kinase/Akt pathway negatively regulates Nod2-mediated NF-kappaB pathway. Biochem. Pharmacol. 2008 Apr 1;75(7):1515-1525. |
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