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Product Name | Recombinant Human Neurotrophin-4 protein (NTF4) (Active) |
Description | Purity > 95% as determined by SDS-PAGE. MW: 59.9kDa. Partial: 23-308aa. C-terminal FC-tagged. Homo sapiens (Human). MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains one Ig-like C1-type domain and is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA is the ligand for NK cell activating receptor KLRK1/NKG2D. MICA seems to have no role in antigen presentation. MICA leads to cell lysis by binding to KLRK1. |
Size | n/a |
Concentration | n/a |
Applications | RUO |
Other Names | MHC Class I Polypeptide-Related Sequence A; MIC-A; MICA; PERB11.1 |
Gene, Accession, CAS # | MICA, UniProt: Q29983 |
Catalog # | RPC27001 |
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Order / More Info | Recombinant Human Neurotrophin-4 protein (NTF4) (Active) from BIOMATIK |
Product Specific References | n/a |
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