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Product Name | Recombinant Human Neurturin Protein |
Description | Neurturin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Persephin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Neurturin signals through a multicomponent receptor system, composed of RET and one of four GFR α (α1-α4) receptors. Neurturin promotes the development and survival of sympathetic and sensory neurons by signaling through a receptor system composed of RET and GFRα2. The functional form of human Neurturin is a disulfide-linked homodimer, of two 11.8 kDa polypeptide monomers (204 total amino acid residues). Each monomer contains seven conserved cysteine residues, one of which (Cys 69) is used for inter-chain disulfide bridging and the others are involved in intramolecular ring formation known as the cysteine knot configuration. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | Neurturin;NRTN; NTN, NRTN |
Gene, Accession, CAS # | NRTN, UniProt: Q99748 |
Catalog # | PROTQ99748-1 |
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Order / More Info | Recombinant Human Neurturin Protein from BOSTER BIO |
Product Specific References | n/a |
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