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| Product Name | Caspase 8 (FLICE, MASH, Mch5), Active, Recombinant, His-tagged, Human |
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| Description | Purity ≥ 95% by SDS-PAGE. Caspase-8 (also known as FLICE/MASH/Mch5) is a member of the interleukin-1b converting enzyme (ICE) family of cysteine proteases. Like other caspases, caspase-8 also exists in cells as an inactive proenzyme. During apoptosis pro-caspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed form of caspase-8 consists of large and small subunits which associate to form the active enzyme. The active recombinant human |
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| Size | 25 units, 100 units |
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| Concentration | n/a |
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| Applications | Suitable for use in Screening for caspase inhibitors, Studying enzyme regulation, Determining target substrates, and as Positive control in caspase activity assays. Other applications not tested. |
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| Other Names | [Caspase-8; Caspase-8; caspase-8; FADD-like ICE; MACH-alpha-1/2/3 protein; apoptotic protease Mch-5; MACH-beta-1/2/3/4 protein; apoptotic cysteine protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; FADD-homologous ICE/CED-3-like protease; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic |
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| Gene, Accession, CAS # | CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; MCH5; CASP-8; FLICE; MACH, Gene ID: 841, Accession: Q14790.1 |
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| Catalog # | MBS635529 |
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| Order / More Info | Caspase 8 (FLICE, MASH, Mch5), Active, Recombinant, His-tagged, Human from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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