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| Product Name | Recombinant Escherichia coli (strain K12) Crossover junction endodeoxyribonuclease RuvC |
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| Description | 2-173aa; Full Length. MW: 34.62kD. Purity >90% as determined by SDS-PAGE. Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Holliday junction nuclease RuvC; Holliday junction resolvase RuvC] |
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| Gene, Accession, CAS # | ruvC, Gene ID: 946378, Accession: NP_416377.1 |
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| Catalog # | MBS1022799 |
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| Order / More Info | Recombinant Escherichia coli (strain K12) Crossover junction endodeoxyribonuclease RuvC from MYBIOSOURCE INC. |
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| Product Specific References | Resolution of Holliday junctions in Escherichia coli identification of the ruvC gene product as a 19-kilodalton protein.Sharples G.J., Lloyd R.G.J. Bacteriol. 173:7711-7715(1991) Molecular analysis of the Escherichia coli ruvC gene, which encodes a Holliday junction-specific endonuclease.Takahagi M., Iwasaki H., Nakata A., Shinagawa H.J. Bacteriol. 173:5747-5753(1991) A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map.Itoh T., A |
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