| 产品详情 |
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| Product Name | Recombinant Escherichia coli (strain K12) Cytosine deaminase |
| Description | 2-427aa; Full Length. MW: 63.4kD. Purity >90% as determined by SDS-PAGE. Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deamination of isoguanine, a mutagenic oxidation product of adenine in DNA, and of isocytosine. To a lesser extent, also catalyzes the conversion of 5-fluorocytosine (5FC) to 5-fluorouracil (5FU); this activity allow |
| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (Yeast), 0.05 mg (E-Coli), 0.1 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [Cytosine aminohydrolaseIsoguanine deaminase1 ] |
| Gene, Accession, CAS # | codA, Gene ID: 944996, Accession: NP_414871.1 |
| Catalog # | MBS1076859 |
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| Order / More Info | Recombinant Escherichia coli (strain K12) Cytosine deaminase from MYBIOSOURCE INC. |
| Product Specific References | Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase.Danielsen S., Kilstrup M., Barilla K., Jochimsen B., Neuhard J.Mol. Microbiol. 6:1335-1344(1992) A first step in the development of gene therapy for colorectal carcinomacloning, sequencing, and expression of Escherichia coli cytosine deaminase.Austin E.A., Huber B.E.Mol. Pharmacol. 43:380-387(1993) Sequence of minutes 4-25 of Escherichia coli.Chung E., Allen E., Araujo R., Aparicio A.M., Davis |
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