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| Product Name | Recombinant Escherichia coli (strain K12) LexA repressor |
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| Description | 1-202aa; Full Length. MW: 22,358 Da. Purity >90% as determined by SDS-PAGE. Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Escherichia coli (strain K12)] |
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| Gene, Accession, CAS # | lexA, Gene ID: 948544, Accession: NP_418467.1 |
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| Catalog # | MBS1108189 |
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| Order / More Info | Recombinant Escherichia coli (strain K12) LexA repressor from MYBIOSOURCE INC. |
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| Product Specific References | Purified lexA protein is a repressor of the recA and lexA genes.Little J.W., Mount D.W., Yanisch-Perron C.R.Proc. Natl. Acad. Sci. U.S.A. 78:4199-4203(1981) |
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