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| Product Name | Recombinant Escherichia coli (strain K12) Oxygen-insensitive NADPH nitroreductase |
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| Description | 1-240aa; Full Length. MW: 42.8kD. Purity >90% as determined by SDS-PAGE. Reduction of nitroaromatic compounds using NADH. Reduces nitrofurazone by a ping-pong bi-bi mechanism possibly to generate a two-electron transfer product. Major component of the oxygen-insensitive nitroreductase activity in E Coli. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Modulator of drug activity A] |
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| Gene, Accession, CAS # | nfsA, Gene ID: 945483, Accession: NP_415372.1 |
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| Catalog # | MBS1159801 |
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| Order / More Info | Recombinant Escherichia coli (strain K12) Oxygen-insensitive NADPH nitroreductase from MYBIOSOURCE INC. |
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| Product Specific References | A general genetic approach in Escherichia coli for determining the mechanism(s) of action of tumoricidal agentsapplication to DMP 840, a tumoricidal agent.Chatterjee P.K., Sternberg N.L.Proc. Natl. Acad. Sci. U.S.A. 92:8950-8954(1995) Biochemical characterization of NfsA, the Escherichia coli major nitroreductase exhibiting a high amino acid sequence homology to Frp, a Vibrio harveyi flavin oxidoreductase.Zenno S., Koike H., Kumar A.N., Jayaraman R., Tanokura M., Saigo K.J. Bacteriol. 178:4508-4 |
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