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| Antigenic Specificity | SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (Internal Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat, mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.Subcellular location: Cytoplasm. Cell junction ?? synapse. Cell junction ?? synapse ?? postsynaptic cell membrane ?? postsynaptic density. Note: Postsynaptic density of neuronal cells. Extends into the region subjacent to the PSD.Tissue specificity: Widely expressed in brain. Also known as: SH3 and multiple ankyrin repeat domains protein 3, ProSAP2, Proline rich synapse associated protein 2, PSAP2. |
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| Immunogen | A synthetic peptide from the internal region of human SHANK3 (SH3 and multiple ankyrin repeat domains protein 3, ProSAP2) conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | DEL22q13.3|PROSAP2|PSAP2|SCZD15|SPANK-2|Prosap2|AI841104|Shank3b |
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| Gene, Accession # | Gene ID: 85358,58234,59312 |
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| Catalog # | ABIN350831 |
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| Price | |
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| Order / More Info | SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (Internal Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 10591208, 17173049, 11258795, 12504591, 18088087 |
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