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| Product Name | CDH2, 160-724aa, Human, His-tag, Baculovirus |
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| Description | MW: 62.9kDa (574aa) 70-100kDa (SDS-PAGE under reducing conditions). Purity >90% by SDS-PAGE. CDH2, also known as cadherin-2 isoform 1, is a transmembrane, homophilic glycoprotein belonging to the calcium-dependent cell adhesion molecule family. It plays a role in neurons and later was found to also play a role in cardiac muscle and in cancer metastasis. Its loss promotes tumorigenesis by releasing membrane-bound B-catenin, hence stimulating Wnt signaling. It seems to be involved in tumor develop |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Absorbance at 280nm) |
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| Applications | SDS-PAGE |
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| Other Names | [Cadherin-2 isoform 1; CDH2; CD325; CDHN; CDw325; NCAD] |
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| Gene, Accession, CAS # | CDH2, Gene ID: 1000, Accession: NP_001783 |
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| Catalog # | MBS206684 |
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| Order / More Info | CDH2, 160-724aa, Human, His-tag, Baculovirus from MYBIOSOURCE INC. |
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| Product Specific References | Buxton RS., et al. (1992) Semin Cell Biol. 3:157-167.; Rubin B., et al. (2016) Tumour Biol. 37:13545-13555. |
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