| 产品详情 |
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| Product Name | LY-2784544 |
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| Description | LY2784544 is a potent, selective and ATP-competitive JAK2 inhibitor (IC50 = 3 nM). effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. LY2784544 effectively inhibits JAK2V617F-driven signaling and cell proliferation in Ba/F3 cells (IC50= 20 and 55?nM, respectively). In comparison, LY2784544 is much less potent at inhibiting interleukin-3-stimulated wild-type JAK2-mediated signaling and cell proliferation (IC50 = 1183 and 1309?nM, respectively). MW: 469.94. Purity ≥98% |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Gandotinib |
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| Gene, Accession, CAS # | CAS: 1229236-86-5 |
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| Catalog # | B1914-5 |
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| Price | |
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| Order / More Info | LY-2784544 from BIOVISION, INC. |
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| Product Specific References | n/a |
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