| 产品详情 |
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| Product Name | PAOA |
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| Description | A selective HDAC1/3 inhibitor (IC50s = 199 and 69 nM for HDAC1 and HDAC3, respectively); selective for HDAC1 and HDAC3 (IC50 = >1.59 µM for HDAC2, 4, 5, 7, and 8 in a cell-free enzyme assay); improves the metabolic deficit exhibited by murine striatal cells isolated from HdhQ111 knock-in mice in a dose-dependent manner; reduces eye neurodegeneration in D. melanogaster model of Huntington's disease; prevents formation of Htt aggregates in the brain and reduces the cognitive deficits in the N171-82Q mouse model of Huntington's disease |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Histone Deacetylase Inhibitor IV |
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| Gene, Accession, CAS # | CAS: 537034-15-4 |
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| Catalog # | 22942-25 |
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| Price | |
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| Order / More Info | PAOA from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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