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| Product Name | GW 3965 hydrochloride |
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| Description | Selective, orally active non-steroidal agonist for the liver X receptor (LXR). In cell-based reporter gene assays, acts as a full agonist of hLXRα and hLXRβ (EC50 values are 190 and 30 nM respectively). Reduces angiotensin II-mediated increases in blood pressure; up-regulates ABCA1 gene expression and raises circulating HDL levels. Displays potent antiatherogenic activity in mouse models of atherosclerosis. Purity 98%. MW (observed): 618.51 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride |
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| Gene, Accession, CAS # | CAS: 405911-17-3 |
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| Catalog # | 2474/1 |
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| Order / More Info | GW 3965 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19818482, 22323586, 24335393, 24812009, 25184494, 25574839, 27731330, 28926619 |
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