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| Product Name | Recombinant Human Ribonuclease H1 (RNASEH1) |
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| Description | 1-286aa, Full Length. MW: 37.6 kDa. Purity >85% as determined by SDS-PAGE. Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II |
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| Size | 0.05 mg (E-Coli), 0.05 mg (Baculovirus), 0.2 mg (Yeast), 0.05 mg (Mammalian-Cell), 0.1 mg (Baculovirus) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ribonuclease H1 isoform 1; Ribonuclease H1; ribonuclease H1; ribonuclease H1; Ribonuclease H type II] |
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| Gene, Accession, CAS # | RNASEH1, Gene ID: 246243, Accession: NP_002927.2 |
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| Catalog # | MBS1023898 |
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| Order / More Info | Recombinant Human Ribonuclease H1 (RNASEH1) from MYBIOSOURCE INC. |
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| Product Specific References | Human senataxin resolves RNA DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination. Skourti-Stathaki K., Proudfoot N.J., Gromak N. Mol. Cell 42:794-805(2011) |
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