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| Product Name | Sazetidine A dihydrochloride |
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| Description | Subtype-selective α4β2 nicotinic acetylcholine receptor ligand (Ki values are 0.26 and 54 nM at α4β2 and α3β4 receptors respectively). May act as a silent desensitizer or as an agonist, depending on subunit stoichiometry (EC50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo and significantly reduces nicotine self-administration in an experimental rat model. Purity 98%. MW (observed): 333.25 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol dihydrochloride |
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| Gene, Accession, CAS # | CAS: 1197329-42-2 |
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| Catalog # | 2736/10 |
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| Order / More Info | Sazetidine A dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23638015, 24728867, 29587798 |
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