| 产品详情 |
| Edit |   |
|---|
| Product Name | AIM 100 |
|---|
| Description | Potent Ack1 (TNK2) inhibitor (IC50 = 22 nM). Exhibits selectivity for Ack1 over ABL1, BTK, Lck and LYN; exhibits no inhibition of 25 other kinases. Suppresses phosphorylation of Tyr267 of the androgen receptor in prostate cancer cells. Also suppresses growth of radioresistant castration-resistant prostate cancer in xenograft tumors in mice. Purity 98%. MW (observed): 371.43 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 5,6-Diphenyl-N-[[(2S)-tetrahydro-2-furanyl]methyl]furo[2,3-d]pyrimidin-4-amine |
|---|
| Gene, Accession, CAS # | CAS: 873305-35-2 |
|---|
| Catalog # | 4946/50 |
|---|
| Price | |
|---|
| Order / More Info | AIM 100 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 22566699 |
|---|
| 产品资料 |
|
|