| 产品详情 |
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| Product Name | ME 0328 |
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| Description | Inhibitor of PARP-3 (IC50 = 0.89 μM). Displays selectivity for PARP-3 over PARP-1, PARP-2 and other ARDT enzymes (IC50 values are 6.3, 10.8 and >30 μM respectively). Enhances CRISPR-Cas9-mediated HER2 mutation frequency, resulting in increased reduction in proliferation of HER2-positive breast cancer cells. Cell permeable. Purity 98%. MW (observed): 321.37 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide |
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| Gene, Accession, CAS # | CAS: 1445251-22-8 |
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| Catalog # | 5054/50 |
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| Price | |
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| Order / More Info | ME 0328 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 27815036 |
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| 产品资料 |
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