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| Product Name | Zileuton |
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| Description | Orally active 5-lipoxygenase (5-LOX) inhibitor that inhibits LTB4 synthesis (IC50 values are 0.56, 2.3 and 2.6 μM in dog, rat and human blood respectively). Inhibits antigen-induced contraction of tracheal strips in vitro (IC50 = 6 μM) and exhibits antiasthmatic activity in vivo. Also weakly inhibits CYP1A2 (Ki = 66 - 98 μM). Purity 99%. MW (observed): 236.29 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea. ICI D2138 |
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| Gene, Accession, CAS # | CAS: 111406-87-2 |
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| Catalog # | 3308/10 |
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| Order / More Info | Zileuton from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21169551, 22493235, 22688342, 23373707, 24335295 |
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