| 产品详情 |
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| Product Name | ZIP |
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| Description | Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. Control Peptide and Biotinylated Peptide also available.. MW (observed): 1928.4. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | z-Pseudosubstrate inhibitory peptide |
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| Gene, Accession, CAS # | CAS: 863987-12-6 |
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| Catalog # | 2549/1 |
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| Order / More Info | ZIP from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 22185613, 23283171, 25761958, 26157359, 26457205, 26619940, 29093271 |
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