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| Product Name | IMPACT, 1-320aa, Human, His tag, E Coli |
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| Description | MW: 38.9kDa (343aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. IMPACT belongs to the IMPACT family and contains 1 RWD domain. This protein is translational regulator that ensures constant high levels of translation under amino acid starvation and acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. Recombinant human IMPACT protein, fused to His-tag at N-terminus, was expressed in E C |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1.0 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [protein IMPACT; RWDD5] |
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| Gene, Accession, CAS # | IMPACT, Gene ID: 55364, Accession: NP_060909 |
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| Catalog # | MBS205319 |
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| Order / More Info | IMPACT, 1-320aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Habibi,D., et al. (2010) J. Cell. Physiol. 225 (1), 196-205; Pereira,C.M., et al. (2005) J. Biol. Chem. 280 (31), 28316-28323 |
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