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| Product Name | YM 58483 |
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| Description | Blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T cells in vitro. Purity 99%. MW (observed): 421.32 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide. Btp2 |
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| Gene, Accession, CAS # | CAS: 223499-30-7 |
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| Catalog # | 3939/10 |
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| Price | |
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| Order / More Info | YM 58483 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23778292, 25651822 |
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| 产品资料 |
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