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| Product Name | RWJ 67657 |
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| Description | Selective p38α and p38β inhibitor (IC50 values are 1 and 11 μM respectively) that displays no activity at p38γ, p38δ and a range of other kinases. Potently inhibits TNF-α and IL-1β release (IC50 values are 3 and 11 nM respectively) and suppresses HIV-1 replication in T cells in vitro. Displays cardioprotective and anti-inflammatory activity in vivo. Orally active. Purity 98%. MW (observed): 425.5 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol |
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| Gene, Accession, CAS # | CAS: 215303-72-3 |
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| Catalog # | 2999/10 |
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| Price | |
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| Order / More Info | RWJ 67657 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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