产品详情 |
Edit |   |
Antigenic Specificity | DNMT1 |
Clone | W15077A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-DNMT1. DNA (Cytisube-5-)-Methyltransferase 1 (DNMT-1), is an enzyme that has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. This enzyme associates with DNA replication sites in the S phase and methylates CpG residues to maintain the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. In addition to this, it associates with DNA during the G2 and M phases to maintain DNA methylation. Diseases associated with abnormal DNMT-1 function include certain human tumors and developmental abnormalities. There are two transcript encoding different isoforms have been found for this gene. |
Immunogen | Partial human DNMT1 recombinant protein (1-200 a.a.) expressed in E. coli. |
Other Names | DNA (cytosine-5-)-methyltransferase 1, CXXC9, MCMT, AIM, DNMT, HSN1E, ADACADN, m. Hasl |
Gene, Accession # | Gene ID: 1786 |
Catalog # | 687502 |
Price | |
Order / More Info | DNMT1 Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
|
|