| 产品详情 |
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| Product Name | Colchicine |
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| Description | Purity ≥97%. Anti-cancer compound. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Anti-inflammatory compound. Suppresses monosodium urate crystal-induced NLRP3/NALP3 inflammasome-driven caspase-1 activation, IL-1beta processing and release, and L-selectin expression on neutrophils at micromolar concentrations. Blocks the release of a crystal-derived chemotactic factor from neutrophil lysosomes, blocks neutrophil adhesion to, and inhibits monosodium urate crystal-induced production of superoxide anions from neutrophils at nanomolar concentrations. Drug used in treatment of gout, familial Mediterranean fever, pericarditis and Behect's disease. Investigated for its anti-cancer activity. It has a narrow therapeutic index with no clear-cut distinction between nontoxic, toxic and lethal doses, causing substantial confusion amo |
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| Size | 500mg, 1g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC 757, EINECS 200-598-5 |
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| Gene, Accession, CAS # | CAS: 64-86-8 |
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| Catalog # | 44676 |
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| Order / More Info | Colchicine from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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