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| Product Name | ZSTK474, Free Base |
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| Description | Purity ~99%. ZSTK474, a novel s-triazine derivative, binds to the ATP-binding site of Class I phosphatidylinositol 3-kinases (PI3K) and inhibits PI3K activity. ZSTK474 has strong antitumor activities against human cancer xenografts (A549, PC-3 and WiDr) when administered orally to mice. Furthermore, ZSTK474 did not show significant toxicity at the doses tested. Solubility: Soluble in DMSO at 20mg/ml; soluble in ethanol at 2.5mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 1-5uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. |
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| Size | 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ZSTK474, Free Base (2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine, ZSTK-474, C510150) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | Z0886-50 |
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| Price | |
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| Order / More Info | ZSTK474, Free Base from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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