| 产品详情 |
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| Product Name | Z-VAD-FMK (Cell permeable) |
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| Description | Purity ≥95% (HPLC). Cell-permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3-induced cells. Used in apoptosis and inflammasome studies. Synonyms: Z-VAD(OMe)-FMK; Z-Val-Ala-DL-Asp(OMe)-FMK; pan-Caspase Inhibitor |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Z-VAD(OMe)-FMK; Z-Val-Ala-DL-Asp(OMe)-FMK; pan-Caspase Inhibitor |
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| Gene, Accession, CAS # | CAS: 187389-52-2 |
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| Catalog # | 45397 |
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| Order / More Info | Z-VAD-FMK (Cell permeable) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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