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| Product Name | FK 866 hydrochloride |
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| Description | Non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, PBEF1) (Ki = 0.3 nM); inhibits NAD biosynthesis. Induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM). Induces apoptosis in four different neuroblastoma cell lines; also induces autophagy in SH-SY5Y cells. Potentiates the cytotoxic effects induced by etoposide (Cat. No. 1226) and cisplatin (Cat. No. 2251). Purity 98%. MW (observed): 427.97 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide hydrochloride |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 4808/10 |
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| Order / More Info | FK 866 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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