| 产品详情 |
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| Antigenic Specificity | AKT1/3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AKT1/3 Polyclonal Antibody. • Target Background: AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby co |
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| Immunogen | KLH conjugated synthetic peptide derived from human AKT1. Immunogen Range: 445-480/480 |
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| Other Names | AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; Protein kinase B; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha; AKT1; RAC-gamma serine/threonine-protein kinase; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2; PKBG |
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| Gene, Accession # | Gene ID: 207, SwissProt: P31749 |
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| Catalog # | bs-0115R |
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| Price | |
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| Order / More Info | AKT1/3 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Xu, H. et al (2013) BMC cancer 13.1 247. PubMed: 23688241 // Li, Xinxin, et al. (2014) Biosci Rep. PubMed: 25200144 // Xu, C., et al .(2014) J Proteomics Computational Biol. PubMed: not posted yet // Zhao, Yong, et al.(2016) Sci Rep. PubMed: 27883089 // Zhang, Weidong, et al. (2017) Chemosphere. PubMed: 29202267 // Tang et al. (2013) Evid.Based.Complement.Alternat.Me. 2013:820695. PubMed: 23737849 // Zhang et al. (2015) J.Immuno. 195:5404-14. PubMed: 26503952 // Kumar et al. (2016) Am.J.Cancer.Re. 6:894-909. PubMed: 27293987 // Liang et al. (2014) Oncotarge. 5:5798-807. PubMed: 25015565 // Chen et al. (2016) Int.J.Oncol. 48:2063-70. PubMed: 26984633 // Erbas et al. (2014) Iran.J.Basic.Med.Sci. 17:747-52. PubMed: 25729542 |
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