| 产品详情 |
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| Product Name | THIQ |
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| Description | A MC4R agonist that is selective over MC1R, MC3R, and MC5R human receptors expressed in CHO cells (IC50s = 1.2, 2,067, 761, and 326 nM, respectively); activates mutant MCR4s, which have been linked to obesity, in HeLa cells expressing the mutant receptors (EC50s = 0.23, 2.60, 39.7, and 43.6 for Wt, R165Q, C271Y, and N97D, respectively); increases the number of penile erections by 92% in a rat ex copula model of penile erection (5 mg/kg, i.v.); inhibits food intake after overnight fast and decreases nocturnal feeding behavior in mice |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MC-4R 1R 3R 5R Chinese hamster ovary R-165Q R-165-Q C-271Y C-271-Y N-97D |
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| Gene, Accession, CAS # | CAS: 312637-48-2 |
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| Catalog # | 24303-1 |
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| Price | |
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| Order / More Info | THIQ from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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