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Antigenic Specificity | NTAN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity). This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human NTAN1. |
Immunogen | Human NTAN1. |
Other Names | NTAN1; Protein N-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine deamidase |
Gene, Accession # | SwissProt: Q96AB6 |
Catalog # | abx029762 |
Price | |
Order / More Info | NTAN1 Antibody from ABBEXA |
Product Specific References | n/a |