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| Product Name | RKI 1447 dihydrochloride |
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| Description | Potent and selective ROCK inhibitor (IC50 values are 6.2 and 14.5 nM for ROCK2 and ROCK1 respectively); suppresses phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but has no effect on the phosphorylation levels of Akt, MEK, and S6 kinase. Displays anti-invasive and antitumor activities in breast cancer cells. Purity 99%. MW (observed): 399.29 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 5061/50 |
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| Price | |
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| Order / More Info | RKI 1447 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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