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| Product Name | Autotaxin Inhibitor Screening Assay Kit |
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| Description | Autotaxin (ATX, Ectonucleotide Pyrophosphatase/Phosphodiesterase-2, ENPP-2, Lysophospholipase D) is a secreted lysophospholipase D that catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to generate lysophosphatidic acid (LPA). LPA is a lipid mediator that activates G protein-coupled receptors and induces a variety of biological responses, such as neurogenesis, angiogenesis, smooth-muscle contraction, platelet aggregation, and wound healing. ATX-LPA signaling is involved in a range of pathologies including tumor progression and inflammation. Cayman's Autotaxin Inhibitor Screening Assay provides a convenient method for screening human ATX inhibitors. ATX cleaves bis-(p-nitrophenyl) phosphate liberating p-nitrophenol, a yellow product that is measured at 405-415 nm. |
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| Size | 96 well |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ATX Inhibitor Screening Assay Kit |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 700580-96WELLS |
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| Order / More Info | Autotaxin Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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