| 产品详情 |
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| Product Name | Avagacestat |
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| Description | A potent, orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP to Aβ40 than signaling through Notch (IC50s = 0.30 and 58 nM, respectively); shows good pharmacokinetics in rats, dogs, and humans and passes the blood-brain barrier, reducing plasma, brain, and cerebrospinal fluid Aβ40 levels |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BMS 708163 |
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| Gene, Accession, CAS # | CAS: 1146699-66-2 |
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| Catalog # | 16711-1 |
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| Price | |
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| Order / More Info | Avagacestat from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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