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| Product Name | Avagacestat |
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| Description | Highly potent γ-secretase inhibitor (Aβ40 IC50 = 0.3 nM). Exhibits >137-fold selectivity for amyloid-β precursor protein (APP) processing over Notch. Reduces plasma and brain Aβ40 and Aβ42 levels in vivo. Orally bioavailable. Purity 98%. MW (observed): 520.89 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. BMS-708163 |
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| Gene, Accession, CAS # | CAS: 1146699-66-2 |
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| Catalog # | 6363/5 |
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| Price | |
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| Order / More Info | Avagacestat from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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