产品详情 |
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Antigenic Specificity | Cathepsin L |
Clone | 33/2 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | ascites |
Size | 100ug (sample available) |
Concentration | 100ug/ml. |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse IgG monoclonal antibody for Cathepsin L, cathepsin L1 (CTSL1) detection. Tested with WB, IHC-F in Human;mouse;rat. No cross reactivity with other proteins. No cross reactivity with other proteins. Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization. |
Immunogen | Procathepsin L isolated from the human lung cancer cell line EPLC 32M1. |
Other Names | Cathepsin L1;3.4.22.15;Cathepsin L;Cyclic protein 2;CP-2;Major excreted protein;MEP;Procathepsin L;Cathepsin L1 heavy chain;Cathepsin L1 light chain;Ctsl;Ctsl1; |
Gene, Accession # | CTSL1, UniProt: P07154 |
Catalog # | MA1014 |
Price | |
Order / More Info | Cathepsin L Antibody from BOSTER BIO |
Product Specific References | n/a |
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