产品详情 |
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Antigenic Specificity | CD213a1 |
Clone | SS12B |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD213a1 (IL-13Rα1). CD213a1, also known as IL-13Rα1, is a subunit of the IL-13R complex. It can heterodimerize with IL-4R and bind IL-13 with high affinity. IL-13Rα1 by itself binds IL-13 with low affinity compared to IL-13Rα2. It is a 48.7 kD, single pass type I membrane protein. It is expressed at low levels on myeloid cells and on activated T and B cells and Th17 cells. It interacts with TYK2 and may lead to activation of JAK1, STAT3, and STAT6 that is induced by IL-13 and IL-4. It has been implicated to have a role in asthma and allergic responses. |
Immunogen | Recombinant extracellular domain of human IL-13 receptor α1 chain |
Other Names | IL-13Ra, CD213a1, NR4, CT19, IL13Ra1, IL-13R alpha 1, CD213 alpha 1 |
Gene, Accession # | Gene ID: 3597 |
Catalog # | 360402 |
Price | |
Order / More Info | CD213a1 Antibody from BIOLEGEND |
Product Specific References | n/a |
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