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| Product Name | PicoProbe™ Malate Dehydrogenase Activity Assay Kit (Fluorometric) |
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| Description | Malate Dehydrogenase (MDH) (EC 1.1.1.37) reversibly converts L-Malate into oxaloacetate in the presence of NAD+. In eukaryotic cells, malate dehydrogenase has 2 isoforms, MDH1 and MDH2. MDH1 is cytosolic and participates in the malate-aspartate shuttle, which transports malate into the mitochondria. Malate will then be utilized for the generation of ATP. MDH2, on the other hand, is a mitochondrial enzyme that participates in the citric acid cycle. MDH2 activity is increased in some neurodegenerative diseases such as Alzheimer's disease, and abnormal MDH activity in serum can serve as a diagnostic tool for severe liver damage (e.g. Hepatocellular carcinoma). Biovision's PicoProbe™ Malate Dehydrogenase Activity Assay Kit (Fluorometric) |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | • Measurement of malate dehydrogenase activity in various tissues/cells• Analysis of citric acid cycle and malate-asparate shuttle |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | K538-100 |
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| Order / More Info | PicoProbe™ Malate Dehydrogenase Activity Assay Kit (Fluorometric) from BIOVISION, INC. |
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| Product Specific References | n/a |
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