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| Antigenic Specificity | Fas |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100ug (sample available) |
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| Concentration | 500ug/ml. |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for Tumor necrosis factor receptor superfamily member 6(FAS) detection. Tested with WB in Rat. No cross reactivity with other proteins. FAS(also known as surface antigen APO1 or CD95) is a member of the tumour-necrosis receptor factor family of death receptors. It acts as an inducer of both neurite growth in vitro and accelerated recovery after nerve injury in vivo. Fas antigen is expressed and functional on papillary thyroid cancer cells and this may have potential therapeutic significance. The FAS antigen shows structural homology with a number of cell surface receptors, including tumor necrosis factor(TNF) receptors and the low-affinity nerve growth factor receptor(NGFR) and is mapped to 10q24.1. And the FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. |
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| Immunogen | E.coli-derived rat Fas recombinant protein (Position: Q22-E324). Rat Fas shares 52% and 61% amino acid (aa) sequences identity with human and mouse Fas, respectively. |
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| Other Names | Tumor necrosis factor receptor superfamily member 6;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;FASLG receptor;CD95;Fas;Apt1, Tnfrsf6; |
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| Gene, Accession # | FAS, UniProt: Q63199 |
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| Catalog # | PB9180 |
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| Price | |
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| Order / More Info | Fas Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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