| 产品详情 |
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| Product Name | Sunitinib malate |
| Description | Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models. Purity 99%. MW (observed): 532.56 |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt. SU 11248 |
| Gene, Accession, CAS # | CAS: 341031-54-7 |
| Catalog # | 3768/50 |
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| Order / More Info | Sunitinib malate from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24550330, 24759231, 25353068, 25943352 |
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