| 产品详情 |
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| Antigenic Specificity | Adipolean (Variant) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA,Blocking Antibody (Inhibition),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The adipolean variant is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. It stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. The adipolean variant antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. |
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| Immunogen | Adipolean Variant antibody was raised in rabbit using highly pure recombinant human adipolean variant as the immunogen. |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN636638 |
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| Price | |
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| Order / More Info | Adipolean (Variant) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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