产品详情 |
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Antigenic Specificity | CHEK2 |
Clone | 4F10 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | ELISA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-CHEK2 Recombinant Antibody (4F10). This product is antibody recognizes CHEK2. The antibody 4F10 immunoassay techniques such as: ELISA, WB. In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p |
Immunogen | n/a |
Other Names | Checkpoint Kinase 2; CHK2 Checkpoint Homolog; Cds1 Homolog; HuCds1; RAD53; HCds1; CDS1; CHK2; Serine/Threonine-Protein Kinase Chk2; |
Gene, Accession # | Gene ID: 11200, UniProt: O96017 |
Catalog # | CBMAB-C6906-LY |
Price | |
Order / More Info | CHEK2 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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