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| Product Name | FTI-277 hydrochloride |
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| Description | MW: 484.07. Purity ≥98% by HPLC. Background: FTI-277 is a potent and selective farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM). It potently inhibits (IC?? = 100 nM) H-Ras, but not the geranylgeranylated Rap1A processing in whole cells. FTI-277 blocks constitutive activation of mitogen-activated protein kinase (MAPK) in H-RasF, but not H-RasGG, or Raf-transformed cells. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester hydrochloride] |
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| Gene, Accession, CAS # | CAS: 180977-34-8 |
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| Catalog # | MBS843220 |
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| Order / More Info | FTI-277 hydrochloride from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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