| 产品详情 |
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| Antigenic Specificity | VISTA |
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| Clone | MIH64 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.5 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VISTA Monoclonal Antibody (MIH64), APC, eBioscience™. VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-H1, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans VISTA is expressed predominantly on hematopoietic cells with the highest densities on CD11b+ myeloid cells, and somewhat lower levels on CD4 and CD8 T cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. Mice deficient in VISTA are viable and have elevated frequencies of activated T cells but do not spontaneous |
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| Immunogen | n/a |
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| Other Names | B7-H5, PD-H1 |
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| Gene, Accession # | Entrez: 74048; Uniprot: Q9D659 |
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| Catalog # | 17-1083-80 |
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| Price | |
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| Order / More Info | VISTA Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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