| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | VISTA |
|---|
| Clone | B7H5DS8 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | PE-Cyanine7 conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.125 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | VISTA Monoclonal Antibody (B7H5DS8), PE-Cyanine7, eBioscience™. VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8. |
|---|
| Immunogen | n/a |
|---|
| Other Names | B7-H5, PD-H1, Gi24, Dies1, SISP1, C10orf54, PD-1H |
|---|
| Gene, Accession # | Entrez: 64115; Uniprot: Q9H7M9 |
|---|
| Catalog # | 25-1088-42 |
|---|
| Price | |
|---|
| Order / More Info | VISTA Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|