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| Product Name | PDE4C, Active |
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| Description | 287-end. MW: ~75 kDa. Description: Recombinant human PDE4C (287-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PDE4C is a member of the phosphodiesterase (PDE) family that is cAMP-specific and has homology to the 'dunce' gene of Drosophila. The 'dunce' gene is one of several genes critical for normal learning and memory in the fly. Homozygous mutations in 'dunce' cause defective short-term memory and behavioral defects (1). PDE4C is a |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | PDE Assay |
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| Other Names | [Homo sapiens phosphodiesterase 4C (PDE4C), transcript variant 1, mRNA; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C; phosphodiesterase 4C; DPDE1; PDE21] |
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| Gene, Accession, CAS # | PDE4C, Gene ID: 5143, Accession: NM_000923.5 |
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| Catalog # | MBS515632 |
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| Order / More Info | PDE4C, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Bolger G, et al: A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Molec. Cell. Biol. 13: 6558-6571, 1993. 2. Baillie G S, et al: Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases. Br J Pharmacol. 2000 Oct;131 (4):811-9. |
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