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| Product Name | SB 223412 |
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| Description | Potent and selective non-peptide NK3 receptor antagonist (Ki values are 1, 144 and >100000 nM for human NK3, NK2 and NK1 receptors respectively). Selective over a panel of >60 receptors, enzymes and ion channels at concentrations of 1 or 10 μM. Inhibits NKB-induced Ca2+ mobilization in vitro (IC50 = 16.6 nM) and inhibits NK3-agonist-induced behavioral responses in vivo. Orally active and brain penetrant. Purity 98%. MW (observed): 382.45 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide |
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| Gene, Accession, CAS # | CAS: 174636-32-9 |
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| Catalog # | 4672/50 |
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| Order / More Info | SB 223412 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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