| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Tim |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | 0.5 mg/ml |
|---|
| Applications | Western blot and Immunohistochemistry (5 µg/ml) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Tim-3 Antibody. As a member of the T cell immunoglobulin and mucin domain (TIM) family, Tim-3 is reported to promote or terminate Th1 immunity and is thought to influence a range of inflammatory conditions. It is constitutively expressed in a subset of murine IFNgamma-secreting Th1 cells, but not Th2 cells, in both human and mice. Additionally, Tim-3 is expressed dendritic cells, and by a subset of CD4+ cells where its levels of expression increase upon anti-CD3/28 stimulation. This molecule is also highly expressed in in vitro polarized Th1 cells, and at lower levels in Th17 cells. It is known to synergize with Toll-like receptors and is thought to regulate Th1 and Th17 cytokine secretion. |
|---|
| Immunogen | Synthetic peptide surrounding amino acid residue 285 of human Tim-3 |
|---|
| Other Names | tim-3, tim3, tim 3, TIMD3, TIMD-3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell membrane protein 3 |
|---|
| Gene, Accession # | Gene ID: 84868, Accession: Q8TDQ0 |
|---|
| Catalog # | 3808-100 |
|---|
| Price | |
|---|
| Order / More Info | Tim Antibody from BIOVISION, INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|