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Product Name | GQ-16 |
Description | Purity >97%. Full activation of peroxisome proliferator-activated receptor gamma (PPAR gamma), e.g., using thiazolidinediones, effectively treats insulin resistance and type 2 diabetes but also commonly promotes weight gain, hyperphagia, and edema. GQ-16 is a partial agonist for PPAR gamma (Ki = 160 nM) which induces adipogenesis significantly less than the full activator rosiglitazone. Like rosiglitazone, GQ-16 reverses high fat diet-mediated impairments in insulin signaling. However, GQ-16 does not induce weight gain, hyperphagia, or edema. GQ-16 does not activate PPAR alpha, PPAR beta / delta, or RXR alpha . |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione |
Gene, Accession, CAS # | CAS: 870554-67-9 |
Catalog # | LS-H80 |
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Order / More Info | GQ-16 from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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