| 产品详情 |
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| Antigenic Specificity | IL-17RB |
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| Clone | 9B10 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-mouse IL-17RB. IL-17RB, also known as IL17RH1, belongs to the cytokine receptor family. IL-17RB possesses a unique intracellular signaling molecule called SEFIR, and is expressed similarily to fibroblast growth factor genes and IL-17R. It is reported to be expressed on iNKT cells, innate lymphoid cells (ILC), and Th2 cells. It binds IL-17B and IL-17E (IL-25) but not IL-17A or C. Its interaction with IL-25 has a higher affinity than that with IL-17B. Binding of IL-17RB and IL-25/IL-17E induces NF-kB mediated IL-8 production through interaction with TRAF6 and Act1. IL-17RB has been reported to play a role in autoimmune diseases such as rheumatoid arthritis and asthma. |
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| Immunogen | Recombinant mouse IL-17RB - Fc chimera (human IgG1) |
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| Other Names | Evi27, IL-17ER, IL17RH1, IL17br, IL-17 receptor B |
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| Gene, Accession # | Gene ID: 50905 |
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| Catalog # | 146302 |
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| Price | |
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| Order / More Info | IL-17RB Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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